Circ-SKA3 Enhances Doxorubicin Toxicity in AC16 Cells Through miR-1303/TLR4 Axis
نویسندگان
چکیده
Doxorubicin (DOX) is a widely used anticancer drug, but its cardiotoxicity largely limits clinical utilization. Circular RNA spindle and kinetochore-associated protein 3 (circ-SKA3) were found to be differentially expressed in heart failure patients. In this study, we investigated the role mechanism of circ-SKA3 DOX-induced cardiotoxicity.
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ژورنال
عنوان ژورنال: International Heart Journal
سال: 2021
ISSN: ['1349-3299', '1349-2365']
DOI: https://doi.org/10.1536/ihj.20-809